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Poxy

Poxy, also known as Experiment 222, is an illegal genetic experiment created by Jumba Jookiba and a character in the Lilo & Stitch franchise. He is designed to act as a virus and infect popular planetary leaders, giving them purple pimples, smelly feet, a swollen right eye, and uncontrollable burping; the symptoms vanish instantly when Poxy leaves his host. He was captured by Gantu (whom he temporarily infected), but was rescued in "Snafu". According to a DVD bonus feature game in Lilo & Stitch 2: Stitch Has a Glitch, his one true place is fixing health issues.

Background

Personality

Poxy is a microscopic experiment that is very devious, yet carefree. He never really worries about anything and is seen multiple times messing with Lilo and Stitch. His worry-free attitude might also be a result of his great confidence. To him, everything seems more of a nuisance than an actual threat because he is unharmed while infecting somebody, not even by antibodies. So, he just makes himself right at home inside his host.

Physical appearance

Poxy is a microscopic experiment whose physiology is akin to a single-celled organism: his body is made of a pale green liquid, exposing several pink organs or organelles, with only a translucent membrane surrounding it. On his main body, he has the standard traits of the other experiments, such as black pupil-less eyes, a large mouth, and a nose. The membrane contains stubby "limbs" extending from it and a few gray-tipped antennae from his "head".

Powers and abilities

Poxy acts like a virus and can enter a victim's body, causing the host to suffer from purple pimples, smelly feet, a swollen right eye, and uncontrollable burping. He can also split his body and bend it around with no effort, implying that he may be a single-celled organism. He displays no need to breathe without air once inside his host, presumably because he filters the oxygen from the host's blood.

Appearances

Lilo & Stitch: The Series

Experiment 222 was the 222nd genetic experiment created by Jumba with Hämsterviel's funding. He was designed to use his disease-transmitting ability to infect popular planetary leaders, resulting in the public revolting against the infected leader. 222 and the other first 624 experiments were deactivated and smuggled to Earth by Jumba during his mission to capture Experiment 626.

All of the experiment pods were released and scattered across the island of Kauai, with 222's pod landing in a sugar crop.

222's pod was caught up in a harvester used to extract sugar cane from the crop. The pod eventually made its way into a box of sugar, which Nani likely bought at a grocery store. Pleakley poured a heap of sugar with 222's pod into his bowl of cereal, the milk added to it activating 222 before it was eaten with the cereal by Pleakley.

When Pleakley later got infected by 222's disease and displayed the above symptoms, he headed off to the nearest health clinic, believing that human doctors could help him. While he sat in the waiting room to be admitted, Gantu showed up looking for 222. He then noticed an ailing Pleakley and chased the latter, since he was afflicted with the experiment.

Fortunately, Lilo and Stitch followed Pleakley to the clinic and managed to rescue him by subduing Gantu with laughing gas. While Gantu was temporarily incapacitated, Lilo and Stitch rushed Pleakley out of the hospital back to their house, where Jumba revealed his ingenious method of removing 222, which would cure Pleakley.

Using Jumba's shrink ray and Nani's dune buggy to aid them, Lilo and Stitch got shrunk to microscopic size and entered Pleakley's body to find and capture 222. After a long chase through Pleakley's body, Lilo and Stitch were able to capture and extract 222 when the latter became stuck in Pleakley's earwax.

Before Lilo and Stitch finished their task and safely exited Pleakley's body, he was kidnapped and imprisoned by Gantu, who later took a beating from a healthy but dysfunctional Pleakley. When Gantu attempted to crush Pleakley afterwards, the former was shrunk to microscopic size and captured by Jumba.

In the end, Lilo planted 222, christened Poxy, inside Gantu, who fell deathly ill. Experiment 625 mocked Gantu about him finally catching an experiment, although the latter protested that he didn't want to actually catch Poxy's virus.

As Gantu was in good health in later episodes, it can be presumed that Poxy was somehow extracted from Gantu's body and sent to Hämsterviel, then back to Gantu in "Woops" along with all of Hämsterviel's other captive experiments after Experiment 600 caused chaos and nearly blew Hämsterviel's cover to the prison guards.

Poxy reappeared in "Snafu", and was freed along with Gantu's other captive experiments by Lilo, Stitch, and several other experiments in a rescue mission. 

Leroy & Stitch

Despite not physically appearing, the first 624 experiments, presumably including Poxy, were rounded up by Leroy and taken to a stadium to be destroyed. However, Lilo, Stitch, Jumba, Pleakley, Reuben, and Gantu arrived before the experiments could be destroyed.

It is unknown whether or not Poxy participated in the following battle between the experiments and the Leroy clones.

The Leroys soon gained the upper hand in the battle, but were defeated when Lilo, Stitch, Reuben, and several other experiments performed the song "Aloha ʻOe", which caused the Leroy army to shut down due to the original Leroy's fail-safe.

Gallery

The Disney Wiki has a collection of images and media related to Poxy.

Trivia

  • Poxy's design was first revealed in a bonus feature trivia game on the original Lilo & Stitch DVD before he officially debuted in Lilo & Stitch: The Series. He was the only one of the three experiments seen in that game who appeared in the show; the other two remain unconfirmed.
  • Poxy also appeared in a DVD bonus feature of Stitch! The Movie in the experiment gallery.
  • Poxy is the smallest known experiment ever created by Jumba.
  • Poxy's pod color is green.
  • In his debut, Poxy was microscopic size. However, in "Snafu", he was the standard size of an experiment. This might imply that he can change size while functioning as a germ, but it is also possible that his container somehow acted like a lens and magnified him to a noticeable size, as he disappeared when he was released.
  • Poxy's holographic silhouette appeared in both "Amnesio" and "Fibber".
  • Poxy was possibly mentioned in "Skip" by Gantu as a small green one, when he was telling Hämsterviel which experiments he caught.
  • Poxy did not appear in Leroy & Stitch, most likely due to his microscopic size.


v - e - d
Media
Films: Lilo & Stitch (video/soundtrack) • Stitch! The Movie (video) • Lilo & Stitch 2: Stitch Has a Glitch (video) • Leroy & Stitch (video) • Lilo & Stitch (2025 film)

Shorts: The Origin of StitchOnce Upon a Studio
Shows: Lilo & Stitch: The SeriesStitch!Stitch & AiChibi Tiny Tales
Soundtracks: Lilo & Stitch: Island FavoritesLilo & Stitch Hawaiian Album
Video Games: Lilo & Stitch (GBA)Lilo & Stitch PinballLilo & Stitch: Hawaiian AdventureLilo & Stitch: Trouble in ParadiseDisney's Stitch: Experiment 626Lilo & Stitch's Island of AdventuresLilo & Stitch 2: Hämsterviel HavocKingdom Hearts IIStitch JamKingdom Hearts: Birth by SleepMotto! Stitch! DSStitch! Super ChefStitch!Now (Stitch Cosplay) • Bomberman: Disney Stitch EditionDisney Magical WorldDisney InfinityDisney Infinity: 2.0 EditionDisney Magical World 2Disney Magic KingdomsDisney Emoji BlitzDisney Crossy RoadDisney Heroes: Battle ModeKingdom Hearts IIIDisney Epic QuestDisney Getaway BlastDisney Dreamlight ValleyDisney SpeedstormTwisted Wonderland
Books: Comic Zone Volume 1: Disney's Lilo & StitchStitch & the SamuraiAgent Stitch

Disney Parks
Disney Animation BuildingDisney Friends of the MonthInnoventionsIt's a Small WorldKaribuni MarketplaceStitch's Great Escape!Stitch EncounterThe Enchanted Tiki Room: Stitch Presents Aloha e Komo Mai!

Entertainment: Lilo & Stitch's Ohana LuauDisney Adventure Friends CavalcadeDisney's Showtime SpectacularDisney's WishesFantasmic!Max LIVE: Gettin’ Goofy With ItMickey and the Magical MapOne Man's Dream II: The Magic Lives OnMickey presents: "Happy Anniversary Disneyland Paris"Stitch's Interplanetary Beach Party BlastStitch's Supersonic CelebrationThe Golden Mickeys
Parades: A Million Splashes of ColourDisney's Dreams On Parade: Moving OnFlights of Fantasy ParadeHappiness is Here ParadeJubilation!Mickey's New Year's Eve ParadeMove It! Shake It! Dance and Play It! Street PartyMickey's Storybook Express
Fireworks: Celebrate the MagicDisney Tales of MagicIlluminate! A Nighttime CelebrationCelebrate! Tokyo DisneylandMomentousWonderful World of AnimationWondrous Journeys
Spring: Disney's Easter WonderlandDisney's Spring PromenadeFashionable Easter
Summer: Adventure is Out There!Mickey's WaterWorksStitch's Summer Dance BashStitch and Friends Summer SurpriseSummer Blast
Halloween: Halloween Pop'n LIVERe-Villains! Halloween ParadeScream and Shout Halloween Parade
Christmas: A Totally Tomorrowland ChristmasDisney Christmas StoriesWorld of Color: Season of Light

Characters
Original: StitchLilo PelekaiNani PelekaiJumba JookibaPleakleyDavid KawenaCaptain GantuJacques von HämstervielGrand CouncilwomanGalactic ArmadaUGF TroopersMertle EdmondsElena, Teresa, and YukiSusan HegartyCobra BubblesMoses PulokiMrs. HasagawaMr. and Mrs. PelekaiLukiIce Cream Man

TV series: Mr. WongMrs. EdmondsStacy EdmondsOfficer KahikoKeoni JamesonMr. JamesonVictoriaMrs. PleakleyPixley PleakleyBertley PleakleyCharles and MaryMitzi Suzuki and Kato StewartMerwin and DeanEllen and LonaZach MakeliRingmasterMayor AnoloNicoléDr. Gladys OkraSaraMr. CooperChaps, Manny, and SperkMortlegax
Stitch!: Yuna KamiharaGrammaPennyKennyTaroSashaHiromanJessicaTigerlily SakaiDoloresAni PelekaiBooGooKijimunaaDelia
Stitch & Ai: Wang Ai LingWang JiejieMeiyingQian DahuWang DaiyuMr. DingBaoDim LongScratchJaboodieJumba's Chinese Experiments
Video game characters: Dr. Habbitrale
Experiments: ChopsueySparkyReubenJamDiggerMaryHuggoSlimyRichterPhantasmoClipMr. StenchySpookyHolioCannonballGigiYinYangKixxSplodyheadAmnesioSwirlyFibberTankSproutElasticoYaarp627DeforestatorZapTopperMeltyHoudiniFudgySinkerNosyFinderSlushyDupeHeatThresherPlasmoidHammerfaceShortstuffAngelFelixPoxyHunkahunkaSampleBabyfierBonnieClydeSluggerDrowsySpikeSqueakFrenchfrySwapperShoeBackhoePokiSlickSkipClinkCheckersPJPlootSnootyRetroBelleMorpholomewSpatsHecklerWishy-WashyPhoonBugbyShushLaxRemmyDoubledipGotchuForeheadHockerZawpMulchShredderPixBoomerMannersWoodyWrapperBlowhardDerrickAceGlitchWoopsSnafuNosoxStamenTickle-TummyLinkLeroyCloudyStopgoSplatSproingKernelCarmenZeroShrinkBraggMrs. SicklyPopDorkifierWormholeToonsHertz DonutWelkoLoriderWitchSproutlingSkunkunaDark End
Guest Characters: Kim PossibleRon StoppableWadeDr. DrakkenShegoRufusPenny ProudOscar ProudTrudy ProudBeBe & CeCe ProudSuga MamaPuffT.J. DetweilerVince LaSalleAshley SpinelliGretchen GrundlerMikey BlumbergGus GriswaldMuriel FinsterJake LongLuong Lao ShiFu DogTrixie CarterArthur Spudinski
Remake: StitchLilo PelekaiNani PelekaiDavid KawenaCobra BubblesMrs. Kekoa
Others: Elvis PresleyPudgeJimmy the CockroachVarious AliensLeroy ClonesYamato MeisonSergeant C4703BK2704-90210

Episodes
Season One: "Richter" • "Phantasmo" • "Clip" • "Mr. Stenchy" • "Spooky" • "Holio" • "Cannonball" • "Yapper" • "Yin-Yang" • "Kixx" • "Splodyhead" • "Amnesio" • "Swirly" • "Fibber" • "Tank" • "Sprout" • "Elastico" • "Yaarp" • "627" • "The Asteroid" • "Topper" • "Melty" • "Houdini" • "Sinker" • "Nosy" • "Finder" • "Slushy" • "Dupe" • "Shortstuff" • "Angel" • "Felix" • "Poxy" • "Hunkahunka" • "Sample" • "Babyfier" • "Bonnie & Clyde" • "Slugger" • "Bad Stitch" • "Drowsy"

Season Two: "Spike" • "Frenchfry" • "Swapper" • "Shoe" • "Slick" • "Skip" • "Checkers" • "PJ" • "Ploot" • "Snooty" • "Retro" • "Belle" • "Morpholomew" • "Spats" • "Heckler" • "Wishy-Washy" • "Phoon" • "Bugby" • "Rufus" • "Shush" • "Lax" • "Remmy" • "Mrs. Hasagawa's Cats/Ace" • "Glitch/Woops" • "Snafu" • "Link"

Songs
He Mele No LiloHeartbreak HotelStuck on YouSuspicious Minds(You're the) Devil in DisguiseHawaiian Roller Coaster RideAloha ʻOeHound DogBurning LoveCan't Help Falling in LoveLahainaRubberneckin'I Need Your Love TonightA Little Less ConversationAlwaysSlicin' SandAloha, E Komo MaiI'm So Lonesome I Could CryJailhouse RockDon't Be Cruel
Locations
HawaiiHonoluluKokaua TownLahui BeachLilo's HouseAloha Animal RescueHasagawa FruitsKaiāulu HaleMertle's HouseBirds of Paradise HotelKilauea LighthouseRental HutMuscle BayKiki's Coffee HutBeauty ParlorMartMacki Macaw'sLuki's Shave IceJumba & Pleakley's Bed & Not BreakfastWaialeale PeakKauai AirportTuroPlorgonarPrison Asteroid K-37Galaxy Defense IndustriesLihue AirportIzayoi IslandIzayoi Elementary School
Objects
Experiment PodsExperiment Pod ContainerJumba's ComputerPlasma BlasterNet CannonGalactic CommunicatorPrison CapsuleFusion ChamberTime MachineReducer RayProtoplasmic Growth RayPlasmatic EnglobulatronScrumpLilo's Experiment BookStitch's SpacesuitStitch's NecklaceChitama Spiritual StoneGood Deed Counter
Vehicles/Spaceships
Jumba's ShipGantu's ShipPolice CruisersThe Red OneDr. Hämsterviel's ShipManta ShuttleHovercraftX-BuggyFederation ShipB.R.B. 9000G.A.C.C. Ship
See Also
Unconfirmed ExperimentsTantalog languagePelekai ʻohana"The 747 Sequence"Stitch Crashes DisneyStitch Attacks Snacks