Season 2 of The League first aired on FX September 16th, 2010. It was written by Jeff Schaffer and Jackie Marcus Schaffer, and directed by Jeff Schafer. The series centered around a Fantasy Football league consisting of five men, Pete, Ruxin, Kevin, Taco and Andre, and their lives.
The Second season of The League was the first to run for thirteen episodes, and the last was aired December 9, 2010.

Characters
Main Characters
- Mark Duplass as Pete (13 episodes)
- Nick Kroll as Ruxin (13 episodes)
- Jon Lajoie as Taco (13 episodes)
- Stephen Rannazzisi as Kevin (13 episodes)
- Paul Scheer as Andre (13 episodes)
- Katie Aselton as Jenny (13 episodes)
Recurring / Minor Characters
- Chad Johnson (Ochocinco) as Himself (1 episode)
- Alison Becker as Darcy (1 episode)
- Janina Gavankar as Shiva (1 episode)
Episodes
"Vegas Draft" September 16, 2010
"Bro-Lo El Cuñado" September 23, 2010
"The White Knuckler" September 30, 2010
"The Kluneburg" October 7, 2010
"The Marathon" October 14, 2010
"The Anniversary Party" October 21, 2010
Ruxin throws an anniversary party for Sofia on the same day as [[[Jenny MacArthur|Jenny's]] birthday, which complicates matters for Kevin. Meanwhile, Meegan (Leslie Bibb) returns with a "plus one."
"Ghost Monkey" October 28, 2010
"The Tie" {{{airdate}}}
"The Expert Witness" November 11, 2010
"High School Reunion" November 18, 2010
"Ramona Neopolitano" December 2, 2010
"Kegel the Elf" December 9, 2010
Tension mounts as Christmas---and the playoffs---near: Ruxin's revenge gift to Kevin backfires; and Ellie's school behavior causes Jenny to worry that Fantasy Football is causing her to neglect her parental duties. Meanwhile, Taco's eggs turn 1 year old.
"The Sacko Bowl" December 9, 2010