Iowa is a part of the United States of America.
- Bill Smith, a contestant in the Sesame Street game show "The Remembering Game," is from Cedar Rapids, Iowa.
- In episode 3858 of Sesame Street, after the Jacket Fairy brings Zoe's jacket to life, he leaves to grant a wish for a pair of jeans in Des Moines, Iowa (explaining that he's also the Pants Fairy).
- On February 15, 2005, Rosita and Elmo hosted a Healthy Minute for the Iowa Communications Network (ICN). They appeared alongside Iowa Senator Tom Harkin to discuss integrating healthy food and exercise into the daily lives of Iowa students.
- In the Sesame Street sketch, "American I", the final contestant, a letter I, comes from an alphabet in Iowa.
- In various interviews, Frank Oz has said Miss Piggy was born on an Iowa farm before seeking out fame and fortune.
- The National Mississippi River Museum in Dubuque, Iowa displayed the Smithsonian Institution's Kermit the Frog puppet as part of their 2005 exhibit "Toadally Frogs".
- In 2019, the Iowa State Fair would celebrate Iowa PBS and Sesame Street's 50th Anniversary by featuring butter sculptures of Big Bird, Oscar the Grouch, Bert, Ernie, Elmo, Cookie Monster, Julia and Abby Cadabby alongside the famous butter cow.