Nero could refer to:
- Characters:
- Nero (Romulan), a Romulan miner native to the 24th century.
- Nero (mirror), a mirror counterpart of Nero, in an alternate mirror universe.
- Nero (Emperor), an emperor of Earth's ancient Roman Empire.
- Jennifer Nero, a 24th century Human.
- Media:
- Star Trek: Nero, a comic book miniseries focusing on the Romulan Nero.
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