Earth-42

This world never had its Spider-Man because its Radioactive Spider was teleported into another reality, which consequentially led to rampant crime and allowed this universe's Sinister Six to form a cartel. Captain Jefferson Morales had passed away, leaving Aaron Davis to help raise his nephew Miles G. Morales, who eventually became this world's Prowler.

After an alternate Miles Morales accidentally travelled to this universe, Aaron mistakes Miles for his own and takes him to the roof, where following a text, Miles G. (equipped with the Prowler's Suit) ambushed his alternate self. Following the capture of the alternate Miles, Aaron and Prowler took him to Aaron's apartment for interrogation. Prowler revealed himself and threatened his alternate self, putting his armored fist up to the other Miles' head.^[1]

When the Sinister Squadron ambushed Spider-Man(Peter Parker-616), Madame Web, Spider-Man 2099, and Arana they would end up capturing Miguel and take him here. The Spider-Society would then go to this universe with plans to rescue him, Jack would torture Miguel in this universe trying to make him give up his secrets until the Society showed up. Miguel then revealed that Kraven the Hunter-Spider was a spy and a traitor, the Sinister Squadron then showed up and attempted to attack the Society but fortunately the door was closed. After defeating Hunter-Spider, they bust out of the roof only to be ambushed by one of their members. To prevent from being defeated they retreated to Earth-71490.^[2]

• The Oz Experiment Arachnid No. 42, the spider which bit Miles Morales in Ultimate Comics Spider-Man #1 had a 42 on it representing its experiment number. On Earth-1610B, the number on the back of the spider that bites Miles Morales represents that it's from Earth-42.