
Factions are organized groups inside the InFamous series that either ally with Cole or try to hinder him.
List of Factions in Infamous
Reapers
- Main article: Reapers

The Reapers were junkies and criminals that took over the Neon District of Empire City after the Blast under the command of Sasha. Soon, citizens of the Neon were added to their ranks through the Black Tar, a mind control agent produced by Sasha. If Cole goes down the evil path, he has the option to work with the faction under their imprisoned leader's influence. The most notable features is that they wear red (or very pale beige, if they are a Conduit) hooded jackets and will vomit Black Tar occasionally. They are the first faction Cole faces. [1]
Dust Men
- Main article: Dust Men

The Dust Men were a gang made up of homeless people under the command of Alden Tate and controlled the Warren District, the lower-income borough of Empire City. This is reflected on their outfits made up of scrap metal and trash bags, earning them the nickname trash baggers, and their guns are covered with rust. Their colors include beige green and brown. They are the second faction Cole faces.[1]
First Sons
- Main article: First Sons

The First Sons were a cult group dedicated to discovering and unlocking the potential of humans through trans humanism. They can be traced back all the way to the 17th century. They controlled the Historic District of Empire City with their leader Kessler. Unlike the other criminal factions of Empire City, they are fully equipped with advanced weaponry and armor, making them the toughest of the three factions. The First Sons wear three piece suits and gas masks with attached tanks. They are the final faction that Cole faces. [1]
Empire City Police Department
- Main article: Empire City Police

The Empire City Police Department were the police force of Empire City and based in all three districts, with their most prominent member being Warden Harms. As Cole fends off most of the other factions, Cole is either able to gain help from the police force (Good karma), or they become another hostile faction to him (Evil Karma).[1]
List of Factions in Infamous 2
The Militia
- Main article: Militia

The Militia were a group of anti-Conduit extremists led by Joseph Bertrand III who enforced an oppressive anti-Conduit agenda in New Marais. Because their are a strict anti-Conduit group, the Militia have no Conduits in their ranks. colors are orange and gray. Mini-gunners are the most noteworthy types.[2] They are the first hostile faction that Cole encounters in Infamous 2.
Vermaak 88
- Main article: Vermaak 88

The Vermaak 88, or the so-called Forced Conduits, were a South African private military company hired by Bertrand for experimentation in his bid to sell them to cause a war between Humans and Consuits. They are clad in metal armor, possess cryogenic abilities, use firearms and are the only faction to only feature Conduits. The Crushers are one of the more notable types of the faction.[2]
The Corrupted
- Main article: Corrupted

The Corrupted were mutated citizens of New Marais created by Bertrand. Their only purpose is to wreak havoc and mayhem all across New Marais in Bertrand's bid to stir up anti-Conduit sentiments and cause a war between Humans and Consuits. They have no normal infantry, oor Conduits. Larger forms include Devourers and Bertrand in his Behemoth form. They are hostile towards all factions as well as Cole.[2]
The Rebels
- Main article: The Rebels

The Rebels are a resistance organization working against the Militia to end their oprressive rule over New Marais. They are one of the factions that don't consist of Conduits, and cooperate with Cole. Cole first stumbles into them when rescuing Rosco Laroche's niece Sara in The Sacrifice.[2]
New Marais Police Department
- Main article: New Marais Police Department

The New Marais Police Department is the police force of New Marais that deliver protection to the city's citizens. As Cole fends off most of the other factions, he is either able to receive help from the police force (Good karma), or gain another hostile faction (Evil karma). The NMPD is also a human faction, like the police department in Empire City, the Rebels and the Militia. Their leader is unknown and there are only two types of officers. They are usually seen patrolling around the streets at random locations.[2]
Vampires
- Main article: Vampires

The Vampires are first introduced in the Festival of Blood standalone game set during the events of inFamous 2. They're the only gang within the series that have both male and female members. They were led of Bloody Mary and it's Cole's mission to exterminate them. The Vampires are not part of the inFamous series' canon.[3]
Trivia
- At one point in time each Empire City Faction Leader (excluding Warden Harms) was a member of the First Sons.
- Sasha is the first, and only female leader in the series, until Second Son, with Brooke Augustine - apart from Bloody Mary, who is not part of the canon - as well as the only leader not seen outside of her fight scene. Though ironically, if one plays the InFamous road, she has the most interaction with him, more than any other leader.
- Both Alden and Sasha hate Kessler, as well as were driven insane because of him. In a Dead Drop message, John mentions that Sasha met with Alden back when she was still a member of the First Sons, for what is never explained.
- None of the faction's members (excluding the Empire City Police, New Marais Police and The Corrupted) faces were ever seen: The Reapers are hidden by their hoods, Dust Men wear bags over their heads, the First Sons wear gas masks, the Militia wear hockey masks or covers it with something else and the Vermaak 88 wear helmets (excluding the Crushers and Ice Titans), although part of a Reaper's face was seen in a concept art/wallpaper and on Cole's Reaper Skin, and a Vermaak 88 conduit's face was also seen in the Rescue Kuo cutscene.
- The Dust Men never speak words, only uttering growls and grunts. It is never explained why they are unable to speak.
- In InFamous 2, every faction has at least one member that at one point is an ally of Cole, whether it be the Ice Gang Ally, Nix's Corrupted or near the very end of InFamous 2, The Militia.
- Festival of Blood is the first game that has female and male gangsters fighting against Cole.
- The gangs in inFAMOUS is similar to that of the original Sly Cooper, in which they're separate, however work together to try and keep Sly from his goal, this is also true for the sequel, as all the gangs are controlled by Joseph Bertrand.