Barbara was the wife of Deacon, and is a mentioned-only character in Fallout 4.
Background
According to her husband, Barbara met Deacon in his younger years, sometime after he left his former synth-hating gang, the University Point Deathclaws, and the two settled down as farmers. Their plans on starting a family and having an honest living were cut short when the gang came after them. The gang had somehow learned that Barbara was in fact a synth herself, something neither she nor Deacon knew before then. Although the gang was able to kill Barbara, Deacon subsequently slaughtered most, if not all of them, in revenge. His grief and regret over Barbara's fate served a large part in his motivation to join the Railroad later in his life and atone by helping other synths escape their slavery to the Institute.[1]
Appearances
Barbara is mentioned only in Fallout 4.