"What are the Dregs?"
"Lost souls drunk on the toxins of the wilds. Usually travelers from other shores, who didn't know a thing about this patch of Sanctuary, and never cared to learn.
They twist the jungle to their needs, squeeze its lifeblood into poisons. They take and take and take. Careful you don't sip from their brews-you might find yourself hooked as they are."
"Lost souls drunk on the toxins of the wilds. Usually travelers from other shores, who didn't know a thing about this patch of Sanctuary, and never cared to learn.
They twist the jungle to their needs, squeeze its lifeblood into poisons. They take and take and take. Careful you don't sip from their brews-you might find yourself hooked as they are."
- The Wanderer and Eru(src)

The Dregs are a monster family in Diablo IV, introduced in Vessel of Hatred. They are found in Nahantu.
Lore
The Dregs are humans who have ventured into the deep parts of the Nahantu jungles. The Dregs began experimenting with eating hallucinogens found in the jungles' flora and/or fauna, sending them into a psychotic rage.[1]
References
- ↑ 2024-08-21, Diablo IV | Vessel of Hatred | Inside the Game | New Region + Game Features. YouTube, accessed on 2024-08-30